I think I would. I'd take it when I was in my very late teens/early twenties and would enjoy having the first hundred and a half or so years being young, next hundred and a half or so years being middle aged and the rest of them slowly edging into old age. Why not? Life IS too short.
As is, I'd STILL take it, even now, at 45 years of age...especially since it would probably reverse a few years off the bod now and leave me looking and feeling like a 20-something again.